Nucleophile-intercepted Beckmann fragmentation reactions

The Electrophile Desolvation Process in Nucleophile - Electrophile Combination Reactions *

where k is the rate constant for a reaction of an electrophile with a given nucleophilic system, k 0 is dependent solely on the identity of the electrophile and N + is a parameter characteristic of the nucleophilic system. The most surprising result of this relation is its incompatibility with the reactivity-selectivity principle, because, since N + is independent of the electrophile, the relat...

Enantioselective Stereodivergent Nucleophile‐Dependent Isothiourea‐Catalysed Domino Reactions

α,β-Unsaturated acyl ammoniums generated from the reaction of α,β-unsaturated 2,4,6-trichlorophenol (TCP) esters bearing a pendent enone with an isothiourea organocatalyst are versatile intermediates in a range of enantioselective nucleophile-dependent domino processes to form complex products of diverse topology with excellent stereoselectivity. Use of either 1,3-dicarbonyls, acyl benzothiazol...

Nuclear Fragmentation Reactions and Heavy-Ion Therapy

Angular Momentum Population in Fragmentation Reactions

A.M. Denis Bacelar, A.M. Bruce, Zs. Podolyák S. Lalkovski, S. Pietri, N. Al-Dahan, M. Górska A. Algora , N. Alkhomashi, J. Benlliure, P. Boutachkov A. Bracco, E. Calore, E. Casarejos, I.J. Cullen A.Y. Deo, P. Detistov, Z. Dombradi , C. Domingo-Pardo M. Doncel, F. Farinon, G.F. Farrelly, H. Geissel W. Gelletly, J. Gerl, N. Goel, J. Grebosz, R. Hoischen I. Kojouharov , N. Kurz, S. Leoni, F. Molin...

Cyclopropenium ion catalysed Beckmann rearrangement.

1-Chloro-2,3-diphenylcyclopropenium ion was found to be a very efficient organocatalyst (3 mol% loading) for liquid phase Beckmann rearrangement of various ketoximes to the corresponding amides/lactams within 2 h in acetonitrile at reflux temperature. This is the first example of the application of the cyclopropenium ion as a catalyst, which opens up a new aspect of the synthetic utility of aro...